DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135.

Abstract

We have investigated DNA-mediated transfer of aminopterin resistance conferred by plasmid and UV resistance conferred by genomic DNA to the Chinese hamster ovary (CHO) cell line UV-135, a UV-sensitive mutant defective in nucleotide excision repair. Plasmid pSV2gpt-CaPO4 coprecipitates induced aminopterin resistance with equal efficiency in the 6-thioguanine… (More)

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@article{Macinnes1984DNAmediatedCO, title={DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135.}, author={Marlene Macinnes and Joshua Bingham and Lee Thompson and G F Strniste}, journal={Molecular and cellular biology}, year={1984}, volume={4 6}, pages={1152-8} }