DNA-mediated control of metal nanoparticle shape: one-pot synthesis and cellular uptake of highly stable and functional gold nanoflowers.

@article{Wang2010DNAmediatedCO,
  title={DNA-mediated control of metal nanoparticle shape: one-pot synthesis and cellular uptake of highly stable and functional gold nanoflowers.},
  author={Zidong Wang and Jieqian Zhang and Jonathan M Ekman and Paul J. A. Kenis and Yi Lu},
  journal={Nano letters},
  year={2010},
  volume={10 5},
  pages={1886-91}
}
The effects of different DNA molecules of the same length on the morphology of gold nanoparticles during synthesis are investigated. While spherical nanoparticles (AuNS) are observed in the presence of 30-mer poly T, like that in the absence of DNA, 30-mer poly A or poly C induces formation of the flower-shaped gold nanoparticle (AuNF). Detailed mechanistic studies indicate that the difference in DNA affinity to the AuNP plays a major role in the different morphology control processes. The DNA… CONTINUE READING

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