DNA mechanics.

C. Benham; S. P. Mielke

DOI:10.1146/annurev.bioeng.6.062403.132016

Corpus ID: 1427671

DNA mechanics.

@article{Benham2005DNAM,
  title={DNA mechanics.},
  author={C. Benham and S. P. Mielke},
  journal={Annual review of biomedical engineering},
  year={2005},
  volume={7},
  pages={
          21-53
        }
}

C. Benham, S. P. Mielke

Published 2005

Medicine

Annual review of biomedical engineering

We review the history of DNA mechanics and its analysis. We evaluate several methods to analyze the structures of superhelical DNA molecules, each predicated on the assumption that DNA can be modeled with reasonable accuracy as an extended, linearly elastic polymer. Three main approaches are considered: mechanical equilibrium methods, which seek to compute minimum energy conformations of topologically constrained molecules; statistical mechanical methods, which seek to compute the Boltzmann… CONTINUE READING

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