DNA integrity in human sperm.

  title={DNA integrity in human sperm.},
  author={Diana Anderson and Małgorzata Maria Dobrzyńska and Tae Won Yu and Loredana Gandini and Eugenia Cordelli and Marcello Span{\^o}},
  journal={Teratogenesis, carcinogenesis, and mutagenesis},
  volume={17 3},
Since the 1970s there have been conflicting reports of decreasing sperm counts in man and increasing testicular cancer. There is a hypothetical link between apparent adverse trends in several measures of human reproductive health and exposure to endocrine disrupters. Rodent bioassays are not suited for the large-scale screening of such chemicals because of their costs, complexity, and ethical concerns. Various in vitro assays have been used to examine the effects of these chemicals, but none… CONTINUE READING