DNA integrity and semen quality in men with low seminal antioxidant levels.

@article{Shamsi2009DNAIA,
  title={DNA integrity and semen quality in men with low seminal antioxidant levels.},
  author={M. B. Shamsi and Sundararajan Venkatesh and Meghana Tanwar and Pankaj Talwar and Rajendra Kumar Sharma and Alok Dhawan and Rajeev Kumar and Narmadā Prasāda Gupta and Neena Malhotra and N Jugindro Singh and Soniya Mittal and Rima Dada},
  journal={Mutation research},
  year={2009},
  volume={665 1-2},
  pages={
          29-36
        }
}
Accurate transmission of information coded in the sperm genome is vital to the pre- and post-natal development of the offspring. Recent advances in reproductive biology have proposed evaluation of sperm DNA integrity as an important assessment tool to infer the presence of DNA strand breaks, numerical abnormalities in sperm chromosome complement, and alterations in the epigenetic regulation of the paternal genome. Oxidative stress (OS), characterized by increased free radicals, may lead to the… CONTINUE READING

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