DNA in nanochannels--directly visualizing genomic information.

Abstract

The power of nanofluidic channels to analyze DNA is described along with practical experimental hints. As an introduction, a general overview is given on conventional DNA analysis tools, as well as tools under development towards the $1000 genome. The focus of this tutorial review is the stretching of DNA in nanoscale channels for coarse-grained mapping of… (More)
DOI: 10.1039/b912918a

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