DNA hypermethylation of tumors from non-small cell lung cancer (NSCLC) patients is associated with gender and histologic type.

@article{Hawes2010DNAHO,
  title={DNA hypermethylation of tumors from non-small cell lung cancer (NSCLC) patients is associated with gender and histologic type.},
  author={Stephen E Hawes and Joshua E. Stern and Qinghua Feng and Linda W. Wiens and Janet S. Rasey and Hiep Lu and Nancy B. Kiviat and Hubert Vesselle},
  journal={Lung cancer},
  year={2010},
  volume={69 2},
  pages={172-9}
}
BACKGROUND We previously identified a number of genes which were methylated significantly more frequently in the tumor compared to the non-cancerous lung tissues from non-small cell lung cancer (NSCLC) patients. Detection of methylation profiles of genes in NSCLC could provide insight into differential pathways to malignancy and lead to strategies for better treatment of individuals with NSCLC. METHODS We determined the DNA methylation status of 27 genes using quantitative MethyLight assays… CONTINUE READING
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