DNA hybridization as a guide to phylogeny: Chemical and physical limits

Abstract

The technique of forming interspecific DNA heteroduplexes and estimating phylogenetic distances from the depression in their duplex melting temperature has several physical and chemical constraints. These constraints determine the maximum phylogenetic distance that may be estimated by this technique and the most appropriate method of analyzing that distance… (More)
DOI: 10.1007/BF02099993

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Cite this paper

@article{Schmid1990DNAHA, title={DNA hybridization as a guide to phylogeny: Chemical and physical limits}, author={C. W. Schmid and Jonathan Marks}, journal={Journal of Molecular Evolution}, year={1990}, volume={30}, pages={237-246} }