DNA from ancient mammoth bones

  title={DNA from ancient mammoth bones},
  author={Erika Hagelberg and Mark George Thomas and Charles E. Cook and Andrei V. Sher and Gennady F. Baryshnikov and Adrian M Lister},

Topics from this paper

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Instability and decay of the primary structure of DNA
The spontaneous decay of DNA is likely to be a major factor in mutagenesis, carcinogenesis and ageing, and also sets limits for the recovery of DNA fragments from fossils. Expand
Recovery of antediluvian DNA
Isolation and characterization of DNA from archaeological bone
  • E. Hagelberg, J. Clegg
  • Biology, Medicine
  • Proceedings of the Royal Society of London. Series B: Biological Sciences
  • 1991
DNA was extracted from human and animal bones recovered from archaeological sites and mitochondrial DNA sequences were amplified from the extracts using the polymerase chain reaction to show that significant amounts of genetic information can survive for long periods in bone. Expand
Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
  • T. Kocher, W. Thomas, +4 authors A. Wilson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1989
The polymerase chain reaction is used to amplify homologous segments of mtDNA from more than 100 animal species, including mammals, birds, amphibians, fishes, and some invertebrates, and the unexpectedly wide taxonomic utility of these primers offers opportunities for phylogenetic and population research. Expand
Proboscidean origins of mastodon and woolly mammoth demonstrated immunologically
For the first time, mastodon bone was found to have elephant-like proteins, which elicited antibodies that reacted strongly with collagen and serum proteins of extant elephants, and the mammoth was doser to Asian and African elephants than to mammals outside the order Proboscidea. Expand