DNA from ancient mammoth bones

  title={DNA from ancient mammoth bones},
  author={Erika Hagelberg and Mark George Thomas and Charles E. Cook and Andrei V. Sher and Gennady F. Baryshnikov and Adrian M. Lister},

Sequencing the nuclear genome of the extinct woolly mammoth

This study shows that nuclear genome sequencing of extinct species can reveal population differences not evident from the fossil record, and perhaps even discover genetic factors that affect extinction.

Data on DNA give evidence for parallel development in mammoths and elephants

Apparently, the lineages of mammoth and living elephants diverged simultaneously from a common ancestor, the greater morphological similarity between the Asian elephant and mammoth is a result of parallel evolution.

Molecular and morphological evidence on the phylogeny of the Elephantidae

The results highlight the need for multiple markers and close attention to within–taxon variation and outgroup selection in both morphological and molecular phylogenetics, and support the mammoth–African elephant relationship.

Descifrando los mensajes del pasado : análisis del ADN antiguo

The results obtained so far are casting some light into the evolutionary processes that took place in the Basque population, and can now test objectively those hypotheses inferred previously based on modern DNA.

Preservation and Recovery of DNA in Postmortem Specimens and Trace Samples

Using DNA analysis, trace biological samples can now be used to determine individual identity, with a vanishingly small probability that the sample derived from any other individual, and developments are having a revolutionary impact on forensic science.

The flickering genes of the last mammoths

The first use of autosomal variation to track the decline of the last mammoths is reported and it is shown that while the Pleistocene‐to‐Holocene transition is associated with a significant reduction in genetic diversity, subsequent levels of variation remain constant until extinction, such a pattern is somewhat surprising.

A statistical appraisal of molecular and morphological evidence for mammoth-elephant relationships

A DNA sequence analysis of the relationship between Mammuthus, Loxodonta and Elephas is presented, and statistical techniques to compare the support for different trees are applied.



Proboscidean origins of mastodon and woolly mammoth demonstrated immunologically

For the first time, mastodon bone was found to have elephant-like proteins, which elicited antibodies that reacted strongly with collagen and serum proteins of extant elephants, and the mastodon was closer to Asian and African elephants than to mammals outside the order Proboscidea.

Recovery of antediluvian DNA

Isolation and characterization of DNA from archaeological bone

  • E. HagelbergJ. Clegg
  • Biology
    Proceedings of the Royal Society of London. Series B: Biological Sciences
  • 1991
DNA was extracted from human and animal bones recovered from archaeological sites and mitochondrial DNA sequences were amplified from the extracts using the polymerase chain reaction to show that significant amounts of genetic information can survive for long periods in bone.

Instability and decay of the primary structure of DNA

The spontaneous decay of DNA is likely to be a major factor in mutagenesis, carcinogenesis and ageing, and also sets limits for the recovery of DNA fragments from fossils.

Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.

The polymerase chain reaction is used to amplify homologous segments of mtDNA from more than 100 animal species, including mammals, birds, amphibians, fishes, and some invertebrates, and the unexpectedly wide taxonomic utility of these primers offers opportunities for phylogenetic and population research.