DNA encapsulation by biocompatible catanionic vesicles.

@article{Rosa2007DNAEB,
  title={DNA encapsulation by biocompatible catanionic vesicles.},
  author={M. Rosa and M. Miguel and B. Lindman},
  journal={Journal of colloid and interface science},
  year={2007},
  volume={312 1},
  pages={
          87-97
        }
}
  • M. Rosa, M. Miguel, B. Lindman
  • Published 2007
  • Chemistry, Medicine
  • Journal of colloid and interface science
  • The encapsulation of DNA by catanionic vesicles has been investigated; the vesicles are composed of one cationic surfactant, in excess, and one anionic. Since cationic systems are often toxic, we introduced a novel divalent cationic amino-acid-based amphiphile, which may enhance transfection and appears to be nontoxic, in our catanionic vesicle mixtures. The cationic amphiphile is arginine-N-lauroyl amide dihydrochloride (ALA), while the anionic one is sodium cetylsulfate (SCS). Vesicles formed… CONTINUE READING
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