DNA dynamics vary according to macrodomain topography in the E. coli chromosome.

  title={DNA dynamics vary according to macrodomain topography in the E. coli chromosome.},
  author={Olivier Esp{\'e}li and Romain Mercier and Fr{\'e}d{\'e}ric Boccard},
  journal={Molecular microbiology},
  volume={68 6},
The organization of the Escherichia coli chromosome has been defined genetically as consisting of four insulated macrodomains and two less constrained regions. Here we have examined the movement of chromosomal loci by tracking fluorescent markers in time-lapse microscopy during a complete cell cycle. Analysing the positioning, the segregation pattern and the motility of markers allowed us to show that the dynamic behaviour of loci belonging to various macrodomains and less constrained regions… CONTINUE READING

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