DNA double-strand breaks after percutaneous transluminal angioplasty.

@article{Geisel2008DNADB,
  title={DNA double-strand breaks after percutaneous transluminal angioplasty.},
  author={Dominik Geisel and Johannes T. Heverhagen and Marc O Kalinowski and H Wagner},
  journal={Radiology},
  year={2008},
  volume={248 3},
  pages={852-9}
}
PURPOSE To determine exemplarily the amount of DNA damage and the repair kinetics after interventional radiologic procedures by using visualization of foci of the phosphorylated form of the H2AX histone variant (gammaH2AX) to quantify DNA double-strand breaks (DSBs) at percutaneous transluminal angioplasty (PTA) of the lower limb arteries. MATERIALS AND METHODS After local ethics committee approval and written informed consent were obtained, five patients (two women, three men; mean age, 64.4… CONTINUE READING

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