DNA degradation with ozone.

  title={DNA degradation with ozone.},
  author={Franco Cataldo},
  journal={International journal of biological macromolecules},
  volume={38 3-5},
  • Franco Cataldo
  • Published 2006 in
    International journal of biological…
DNA was ozonized in solution and the reaction was followed with polarimetry and with iodimetry. Polarimetry was used to determine the molar ratio DNA/O(3) when the DNA optical activity vanishes completely. At a molar ratio DNA/O(3)=2.3 the supramolecular structure of DNA collapses completely. Instead, iodimetry shows that the ozonolysis proceeds until all the nucleobases have been destroyed, an event which occurs at a molar ratio DNA/O(3)=1.1. The ozonolysis of DNA was also followed… CONTINUE READING

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