DNA damage: chemistry, repair, and mutagenic potential.

  • Birgit Singer
  • Published 1996 in Regulatory toxicology and pharmacology : RTP

Abstract

This paper is an overview on the chemical and biochemical effects of three different human carcinogens on DNA in vitro in terms of adducts, their effect on replication, in vitro and in vivo, and their repair by enzymes from human cells. The carcinogenic compounds chosen for specific discussion are N-nitroso alkylating agents: the vinyl chloride metabolite… (More)

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Cite this paper

@article{Singer1996DNADC, title={DNA damage: chemistry, repair, and mutagenic potential.}, author={Birgit Singer}, journal={Regulatory toxicology and pharmacology : RTP}, year={1996}, volume={23 1 Pt 1}, pages={2-13} }