DNA damage, a biomarker of carcinogenesis: its measurement and modulation by diet and environment.

@article{Hwang2007DNADA,
  title={DNA damage, a biomarker of carcinogenesis: its measurement and modulation by diet and environment.},
  author={E S Hwang and Phyllis E. Bowen},
  journal={Critical reviews in food science and nutrition},
  year={2007},
  volume={47 1},
  pages={27-50}
}
Free radicals and other reactive oxygen or nitrogen species are constantly generated in vivo and can cause oxidative damage to DNA. This damage has been implicated to be important in many diseases, including cancer. The assessment of damage in various biological matrices, such as tissues, cells, and urine, is vital to understanding this role and subsequently devising intervention strategies. During the last 20 years, many analytical techniques have been developed to monitor oxidative DNA base… CONTINUE READING
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