DNA content and prognosis of non-Hodgkin's lymphoma.

  title={DNA content and prognosis of non-Hodgkin's lymphoma.},
  author={Douglas R. Morgan and John M. Williamson and Philip Quirke and A. D. Clayden and Morton E. Smith and C O'brien and Deborah Allison and J. Anthony Child and Cameron C Bird},
  journal={British Journal of Cancer},
  pages={643 - 649}
Ninety cases of non-Hodgkin's lymphoma diagnosed prior to the use of modern therapeutic regimens (1963-67) and 88 cases treated with such chemotherapy (1980-85) were studied using conventional morphology and flow cytometry. DNA aneuploidy as determined by flow cytometry was more common among high grade (38%) than low grade (19%) tumours (P less than 0.01). Measurements of proliferative index (S + G2 phase cells) revealed significantly increased values for high grade as compared with low grade… CONTINUE READING

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