DNA complexing antibiotics: daunomycin, adriamycin and their derivatives.

  title={DNA complexing antibiotics: daunomycin, adriamycin and their derivatives.},
  author={Aliceanne Marco and Federico Arcamone},
  volume={25 3},
9-Acetyl-4-methoxy-7,8,9,11-tetrahydroxy-6,7,9,11-tetrahydroxy-o-(3'-amino-2',3',6'-trideoxy-alpha-L-lyxohexopyranoside) (daunomycin, daunorubicin, NSC-82 131, Daunoblasin), 14-hydroxy-daunorubicin (adriamycin, doxorubicin, NSC-123 127, Adriblastin), dihydrodaunomycin, their aglycones and other related compounds represent the group of S. peucetius derived antibiotics. The biosynthetic glycosides as well as some semisynthetic analogues or derivatives form strong complexes with double stranded… CONTINUE READING

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