DNA complexes with block and graft copolymers of N-(2-hydroxypropyl)methacrylamide and 2-(trimethylammonio)ethyl methacrylate.

Abstract

Block and graft copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) with 2-(trimethylammonio)ethyl methacrylate (TMAEM) were synthesized for the preparation of polyelectrolyte complexes with calf thymus DNA intended for targeted delivery of genes in vivo. In this study, the effects of the poly(HPMA) content of copolymers on the parameters of the… (More)

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@article{Oupick1999DNACW, title={DNA complexes with block and graft copolymers of N-(2-hydroxypropyl)methacrylamide and 2-(trimethylammonio)ethyl methacrylate.}, author={David Oupick{\'y} and Cestm{\'i}r Kon{\'a}k and Karsten Ulbrich}, journal={Journal of biomaterials science. Polymer edition}, year={1999}, volume={10 5}, pages={573-90} }