DNA cloning in Streptomyces: resistance genes from antibiotic-producing species

@article{Thompson1980DNACI,
  title={DNA cloning in Streptomyces: resistance genes from antibiotic-producing species},
  author={Charles B. Thompson and Judith M. Ward and David A. Hopwood},
  journal={Nature},
  year={1980},
  volume={286},
  pages={525-527}
}
The biochemical and morphological differentiation of actinomycetes makes them academically and economically interesting. Their secondary metabolites provide the majority of medically and agriculturally important antibiotics1 (streptomycete genes may also be the primary source of clinically important antibiotic resistance2); their complex morphological developmental cycle involves a series of changes from vegetative mycelial growth to spore formation3. Recombinant DNA technology would add a… CONTINUE READING

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