DNA binding to mica correlates with cationic radius: assay by atomic force microscopy.

@article{Hansma1996DNABT,
  title={DNA binding to mica correlates with cationic radius: assay by atomic force microscopy.},
  author={H. G. Hansma and Daniel E. Laney},
  journal={Biophysical journal},
  year={1996},
  volume={70 4},
  pages={1933-9}
}
In buffers containing selected transition metal salts, DNA binds to mica tightly enough to be directly imaged in the buffer in the atomic force microscope (AFM, also known as scanning force microscope). The binding of DNA to mica, as measured by AFM-imaging, is correlated with the radius of the transition metal cation. The transition metal cations that effectively bind DNA to mica are Ni(II), Co(II), and Zn(II), which have ionic radii from 0.69 to 0.74 A. In Mn(II), ionic radius 0.82 A, DNA… CONTINUE READING
54 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

Similar Papers

Loading similar papers…