DNA binding and regulatory effects of transcription factors SP1 and USF at the rat amyloid precursor protein gene promoter.

@article{Hoffman1995DNABA,
  title={DNA binding and regulatory effects of transcription factors SP1 and USF at the rat amyloid precursor protein gene promoter.},
  author={Peter W. Hoffman and J M Chernak},
  journal={Nucleic acids research},
  year={1995},
  volume={23 12},
  pages={2229-35}
}
Two DNA elements which we have termed SAA and GAG have been shown to control expression of the rat amyloid precursor protein (APP) gene, and the region containing the SAA element has been shown to interact with nuclear proteins [Hoffman and Chernak (1994) Biochem. Biophys. Res. Commun. 201, 610-617]. In this report we study DNA sequences and proteins which influence the activity of the SAA element. An oligonucleotide containing the SAA element is specifically bound by nuclear proteins derived… CONTINUE READING

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