DNA-based identification and epidemiologic typing of bacterial pathogens.

@article{Versalovic1993DNAbasedIA,
  title={DNA-based identification and epidemiologic typing of bacterial pathogens.},
  author={James Versalovic and Christopher W. Woods and PaulR. Georghiou and RichardJ. Hamill and James R Lupski},
  journal={Archives of pathology & laboratory medicine},
  year={1993},
  volume={117 11},
  pages={
          1088-98
        }
}
Genotypic, or DNA-based, methods have become increasingly applicable for infectious disease diagnosis and epidemiologic analysis. The ability to assess the pathogen's genotype directly bypasses requirements for cultivation and may diminish diagnostic delays with fastidious organisms. Genotypic typing methods have enhanced epidemiologic studies by providing techniques with greater discriminatory ability and smaller proportions of nontypeable samples. Hence, these methods enable rigorous studies… CONTINUE READING

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