DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans.

@article{Lane2001DNAAS,
  title={DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans.},
  author={Shelley Lane and Charles E. Birse and Shaoyu Zhou and Ryan Matson and Haoping Liu},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 52},
  pages={48988-96}
}
Candida albicans, normally a human commensal, can cause fatal systemic infections under certain circumstances. Its unique ability to switch from yeast to hyphal growth in response to various environmental signals is inherent to its pathogenicity. Filamentation is regulated by multiple pathways including a Cph1-mediated mitogen-activated protein kinase pathway, an Efg1-mediated cAMP/PKA pathway, and a Cph2 pathway. To gain a general picture of how these various signaling pathways regulate… CONTINUE READING
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