DNA analysis using long-term preserved fixed cytogenetic preparations


SummaryDNA was isolated from cell pellets that had been stored in methanol-acetic acid (3 : 1) at −20°C up to 6 years. These cell pellets contained high molecular weight DNA sufficient for Southern blot hybridization. The method enables us to study the DNA of a patient after completing chromosome analysis or in cases where DNA samples are otherwise not… (More)
DOI: 10.1007/BF01897782

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