DNA Vaccine for West Nile Virus Infection in Fish Crows (Corvus ossifragus)

@inproceedings{Turell2003DNAVF,
  title={DNA Vaccine for West Nile Virus Infection in Fish Crows (Corvus ossifragus)},
  author={Michael J. Turell and Michel L. Bunning and George V. Ludwig and Brian L. Ortman and Jeff Chang and Tully J. Speaker and Andrew L Spielman and Robert G. McLean and Nicholas Komar and Robert D. Gates and Tracey S. McNamara and Terry E. Creekmore and Linda Farley and Carl J. Mitchell},
  booktitle={Emerging infectious diseases},
  year={2003}
}
A DNA vaccine for West Nile virus (WNV) was evaluated to determine whether its use could protect fish crows (Corvus ossifragus) from fatal WNV infection. Captured adult crows were given 0.5 mg of the DNA vaccine either orally or by intramuscular (IM) inoculation; control crows were inoculated or orally exposed to a placebo. After 6 weeks, crows were challenged subcutaneously with 105 plaque-forming units of WNV (New York 1999 strain). None of the placebo inoculated-placebo challenged birds died… CONTINUE READING

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