DNA Topoisomerase II Modulates Insulator Function in Drosophila

@inproceedings{Ramos2011DNATI,
  title={DNA Topoisomerase II Modulates Insulator Function in Drosophila},
  author={Edward Ramos and Eduardo A. Torre and Ashley M. Bushey and Baraka V Gurudatta and Victor G Corces},
  booktitle={PloS one},
  year={2011}
}
Insulators are DNA sequences thought to be important for the establishment and maintenance of cell-type specific nuclear architecture. In Drosophila there are several classes of insulators that appear to have unique roles in gene expression. The mechanisms involved in determining and regulating the specific roles of these insulator classes are not understood. Here we report that DNA Topoisomerase II modulates the activity of the Su(Hw) insulator. Downregulation of Topo II by RNAi or mutations… CONTINUE READING
Highly Cited
This paper has 32 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Chromatin insulators: lessons from the fly.

Briefings in functional genomics & proteomics • 2009
View 1 Excerpt

Chromatin loops in gene regulation.

Biochimica et biophysica acta • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…