DNA Sequence Compression Using the Burrows-Wheeler Transform

  title={DNA Sequence Compression Using the Burrows-Wheeler Transform},
  author={Donald A. Adjeroh and Yong Zhang and Amar Mukherjee and Matt Powell and Timothy C. Bell},
  journal={Proceedings. IEEE Computer Society Bioinformatics Conference},
We investigate off-line dictionary oriented approaches to DNA sequence compression, based on the Burrows-Wheeler Transform (BWT). The preponderance of short repeating patterns is an important phenomenon in biological sequences. Here, we propose off-line methods to compress DNA sequences that exploit the different repetition structures inherent in such sequences. Repetition analysis is performed based on the relationship between the BWT and important pattern matching data structures, such as the… CONTINUE READING
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