DNA Replication Licensing Proteins for Early Detection of Lung Cancer

  title={DNA Replication Licensing Proteins for Early Detection of Lung Cancer},
  author={VS Veena and K Rajan and VN Saritha and Preethi Sara George and K Chandramohan and K Jayasree and S Thara and K. Sujathan},
  booktitle={Asian Pacific journal of cancer prevention : APJCP},
Background: To identify and characterize malignant and premalignant cells in sputum and matched tissue samples with reference to expression of minichromosome maintenance proteins (MCM2, MCM5) and cell division cycle protein 6 (CDC 6) and to assess their potential as biomarkers of premalignant and malignant lesions of the lung and associations with clinicopathological features. Methods: Expression of MCM2, MCM5 and 6 proteins in sputum samples and corresponding tissues was assessed by… CONTINUE READING


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