DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples

@article{Simbolo2013DNAQW,
  title={DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples},
  author={M. Simbolo and M. Gottardi and V. Corbo and M. Fassan and A. Mafficini and G. Malpeli and R. Lawlor and A. Scarpa},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
  • M. Simbolo, M. Gottardi, +5 authors A. Scarpa
  • Published 2013
  • Medicine, Biology
  • PLoS ONE
  • Histopathological samples are a treasure-trove of DNA for clinical research. However, the quality of DNA can vary depending on the source or extraction method applied. Thus a standardized and cost-effective workflow for the qualification of DNA preparations is essential to guarantee interlaboratory reproducible results. The qualification process consists of the quantification of double strand DNA (dsDNA) and the assessment of its suitability for downstream applications, such as high-throughput… CONTINUE READING

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