DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples

@inproceedings{Simbolo2013DNAQW,
  title={DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples},
  author={Michele Simbolo and Marisa Gottardi and Vincenzo Corbo and Matteo Fassan and Andrea Mafficini and Giorgio Malpeli and Rita T. Lawlor and Aldo Scarpa},
  booktitle={PloS one},
  year={2013}
}
Histopathological samples are a treasure-trove of DNA for clinical research. However, the quality of DNA can vary depending on the source or extraction method applied. Thus a standardized and cost-effective workflow for the qualification of DNA preparations is essential to guarantee interlaboratory reproducible results. The qualification process consists of the quantification of double strand DNA (dsDNA) and the assessment of its suitability for downstream applications, such as high-throughput… CONTINUE READING
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