DNA Methylation and Histone Acetylation Patterns in Cultured Bovine Adipose Tissue-Derived Stem Cells (BADSCs)

@inproceedings{Abouhamzeh2015DNAMA,
  title={DNA Methylation and Histone Acetylation Patterns in
Cultured Bovine Adipose Tissue-Derived Stem
Cells (BADSCs)},
  author={Beheshteh Abouhamzeh and Mohammad Salehi and A. Khosro Hosseini and Ali Reza Masteri-Farahani and Fatemeh Fadai and Mohammad Heidari and Mohsen Nourozian and Masoud Soleimani and Mohsen Khorashadizadeh and Majid Mossahebi-Mohammadi and Ardalan Mansouri},
  booktitle={Cell journal},
  year={2015}
}
OBJECTIVE Many studies have focused on the epigenetic characteristics of donor cells to improve somatic cell nuclear transfer (SCNT). We hypothesized that the epigenetic status and chromatin structure of undifferentiated bovine adipose tissue-derived stem cells (BADSCs) would not remain constant during different passages. The objective of this study was to determine the mRNA expression patterns of DNA methyltransferases (DNMT1, DNMT3a, DNMT3b) and histone deacetyltransferses (HDAC1, HDAC2… CONTINUE READING
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