DNA Methylation Signature of Childhood Chronic Physical Aggression in T Cells of Both Men and Women

@inproceedings{Guillemin2014DNAMS,
  title={DNA Methylation Signature of Childhood Chronic Physical Aggression in T Cells of Both Men and Women},
  author={Claire Guillemin and Nadine Provençal and Matthew Suderman and Sylvana Cote and F. Vitaro and Mark Hallett and Richard E. Tremblay and Moshe Szyf},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND High frequency of physical aggression is the central feature of severe conduct disorder and is associated with a wide range of social, mental and physical health problems. We have previously tested the hypothesis that differential DNA methylation signatures in peripheral T cells are associated with a chronic aggression trajectory in males. Despite the fact that sex differences appear to play a pivotal role in determining the development, magnitude and frequency of aggression, most of… CONTINUE READING

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