DNA Methylation Profiling in Inflammatory Bowel Disease Provides New Insights into Disease Pathogenesis

  • Ryana, Miriam Tosettoa, +13 authors Therese M. Murphyc
  • Published 2015

Abstract

Background and Aims: Inflammatory bowel diseases (IBDs) are heterogeneous disorders with complex aetiology. Quantitative genetic studies suggest that only a small proportion of the disease variance observed in IBD is accounted for by genetic variation, indicating a potential role for differential epigenetic regulation in disease aetiology. The aim of this… (More)

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