DNA Methylation Patterns in Cord Blood DNA and Body Size in Childhood

@inproceedings{Relton2012DNAMP,
  title={DNA Methylation Patterns in Cord Blood DNA and Body Size in Childhood},
  author={Caroline Relton and Alexandra Groom and Beate St Pourcain and Adrian Sayers and Daniel C. Swan and Nicholas D Embleton and Mark Stephen Pearce and Susan M. Ring and Kate Northstone and Jon H. Tobias and Joseph M. Trakalo and Andrew Robert Ness and S O Shaheen and George Davey Smith},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Epigenetic markings acquired in early life may have phenotypic consequences later in development through their role in transcriptional regulation with relevance to the developmental origins of diseases including obesity. The goal of this study was to investigate whether DNA methylation levels at birth are associated with body size later in childhood. PRINCIPAL FINDINGS A study design involving two birth cohorts was used to conduct transcription profiling followed by DNA methylation… CONTINUE READING