DNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases

@inproceedings{Thomson2014DNAGB,
  title={DNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases},
  author={N. H. Thomson and S{\'e}rgio Santos and Lesley A. Mitchenall and Tanya Stuchinskaya and James A. Taylor and Anthony Maxwell},
  booktitle={Scientific reports},
  year={2014}
}
DNA topoisomerases control the topology of DNA. Type II topoisomerases exhibit topology simplification, whereby products of their reactions are simplified beyond that expected based on thermodynamic equilibrium. The molecular basis for this process is unknown, although DNA bending has been implicated. To investigate the role of bending in topology simplification, the DNA bend angles of four enzymes of different types (IIA and IIB) were measured using atomic force microscopy (AFM). The enzymes… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 7 times over the past 90 days. VIEW TWEETS
5 Citations
50 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 50 references

A method to provide rapid in situ determination of tip radius in dynamic atomic force microscopy

  • S Santos
  • The Review of scientific instruments
  • 2012

Similar Papers

Loading similar papers…