DNA-Binding Motif of the Imprinted Transcription Factor PEG3

  title={DNA-Binding Motif of the Imprinted Transcription Factor PEG3},
  author={Suman Lee and An Ye and Joomyeong Kim and Chun-Hsi Huang},
  booktitle={PloS one},
Peg3 is an imprinted gene that is predicted to encode a DNA-binding zinc finger protein. This was previously demonstrated through Chromatin ImmunoPrecipitation-based Sequencing experiments. In the current study, we reanalyzed the previous ChIP-Seq results and further characterized the DNA-binding motif of PEG3. According to the results, PEG3 binds to the promoters and enhancers of a subset of genes that are closely associated with the known functions of Peg3. Some of these identified targets… CONTINUE READING
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