DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-implications for the fish embryo test (FET).

@article{Kais2013DMSOMT,
  title={DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-implications for the fish embryo test (FET).},
  author={Britta Kais and Katharina E Schneider and Susanne Keiter and Kirsten Henn and Chrisita Ackermann and Thomas Braunbeck},
  journal={Aquatic toxicology},
  year={2013},
  volume={140-141},
  pages={229-38}
}
Since 2007, when REACH came into force, the fish embryo test has received increasing attention as a potential alternative for the acute fish test. Due to its low toxicity and the ability to permeate biological membranes without significant damage to their structural integrity, dimethyl sulfoxide (DMSO) is a commonly used solvent in the fish embryo test. Little is known, however, about the membrane penetration properties of DMSO, the impact of different concentrations of DMSO on the potential… CONTINUE READING

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