DLIGHT - Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework

@inproceedings{Dessimoz2008DLIGHTL,
  title={DLIGHT - Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework},
  author={Christophe Dessimoz and Daniel Margadant and Gaston H. Gonnet},
  booktitle={RECOMB},
  year={2008}
}
This paper presents an algorithm to detect lateral gene transfer (LGT) on the basis of pairwise evolutionary distances. The prediction is made from a likelihood ratio derived from hypotheses of LGT versus no LGT, using multivariate normal theory. In contrast to approaches based on explicit phylogenetic LGT detection, it avoids the high computational cost and pitfalls associated with gene tree inference, while maintaining the high level of characterization obtainable from such methods (species… 
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