DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population.

@article{Noble2005DLG5VD,
  title={DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population.},
  author={Colin L. Noble and Elaine R. Nimmo and Hannah Drummond and Leonard Smith and Ian D. R. Arnott and Jack Satsangi},
  journal={Gut},
  year={2005},
  volume={54 10},
  pages={1416-20}
}
INTRODUCTION Recent data have suggested that specific haplotypic variants of the DLG5 gene on chromosome 10q23 may be associated with susceptibility to inflammatory bowel disease (IBD) in Germany. Haplotype D, notably characterised by the presence of a G-->A substitution at nucleotide 113, was associated with susceptibility to Crohn's disease (CD) whereas an extended haplotype A conferred protection. AIMS Association of DLG5 haplotypic variants with disease susceptibility, genotype-phenotype… CONTINUE READING

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NOD 2 / CARD 15 , TLR 4 and CD 14 mutations in Scottish and Irish Crohn ’ s disease patients : evidence for genetic heterogeneity within Europe ?

  • ID Arnott, ER Nimmo, HE Drummond
  • Genes Immun
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