DL-ethionine treatment of adult pancreatic donors. Amelioration of diabetes in multiple recipients withe tissue from a single donor.

Abstract

Transplantation of adult rat pancreatic islet tissue as a free graft requires the separation of islet from exocrine tissue to avoid host injury or graft destruction by digestive enzymes. The poor yield from islet isolation techniques currently necessitates the use of multiple donors to ameliorate diabetes in a single recipient. DL-ethionine (DLE) is an… (More)

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@article{Payne1979DLethionineTO, title={DL-ethionine treatment of adult pancreatic donors. Amelioration of diabetes in multiple recipients withe tissue from a single donor.}, author={William D. Payne and David E. Sutherland and Arthur J. Matas and Philip Gorecki and John Najarian}, journal={Annals of surgery}, year={1979}, volume={189 2}, pages={248-56} }