DISCOVER: a feature-based discriminative method for motif search in complex genomes


MOTIVATION Identifying transcription factor binding sites (TFBSs) encoding complex regulatory signals in metazoan genomes remains a challenging problem in computational genomics. Due to degeneracy of nucleotide content among binding site instances or motifs, and intricate 'grammatical organization' of motifs within cis-regulatory modules (CRMs), extant… (More)
DOI: 10.1093/bioinformatics/btp230


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