DING proteins: numerous functions, elusive genes, a potential for health

@article{Bernier2013DINGPN,
  title={DING proteins: numerous functions, elusive genes, a potential for health},
  author={François Bernier},
  journal={Cellular and Molecular Life Sciences},
  year={2013},
  volume={70},
  pages={3045-3056}
}
DING proteins, named after their conserved N-terminus, form an overlooked protein family whose members were generally discovered through serendipity. It is characterized by an unusually high sequence conservation, even between distantly related species, and by an outstanding diversity of activities and ligands. They all share a demonstrated capacity to bind phosphate with high affinity or at least a predicted phosphate-binding site. However, DING protein genes are conspicuously absent from… CONTINUE READING

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