DICAM inhibits angiogenesis via suppression of AKT and p38 MAP kinase signalling.

Abstract

AIMS Dual Ig domain-containing adhesion molecule (DICAM), a protein with homology to the junctional adhesion molecule family, has been demonstrated to interact with integrin αVβ3 that plays a critical role in angiogenesis. Here, we determined the role of DICAM during angiogenesis and the molecular mechanisms involved in the inhibition of angiogenesis… (More)
DOI: 10.1093/cvr/cvt019

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6 Figures and Tables