DIANA - algorithmic improvements for analysis of data-independent acquisition MS data

@article{Teleman2015DIANAA,
  title={DIANA - algorithmic improvements for analysis of data-independent acquisition MS data},
  author={Johan Teleman and Hannes L. R{\"o}st and George Rosenberger and Uwe Schmitt and Lars Malmstr{\"o}m and Johan Malmstr{\"o}m and Fredrik Levander},
  journal={Bioinformatics},
  year={2015},
  volume={31 4},
  pages={555-62}
}
MOTIVATION Data independent acquisition mass spectrometry has emerged as a reproducible and sensitive alternative in quantitative proteomics, where parsing the highly complex tandem mass spectra requires dedicated algorithms. Recently, targeted data extraction was proposed as a novel analysis strategy for this type of data, but it is important to further develop these concepts to provide quality-controlled, interference-adjusted and sensitive peptide quantification. RESULTS We here present… CONTINUE READING

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