DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.

@article{Villareal2006DHEAEE,
  title={DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.},
  author={Dennis T. Villareal and John O. Holloszy},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2006},
  volume={291 5},
  pages={
          E1003-8
        }
}
  • D. VillarealJ. Holloszy
  • Published 1 November 2006
  • Medicine
  • American journal of physiology. Endocrinology and metabolism
The plasma levels of dehydroepiandrosterone (DHEA) and its sulfated form (DHEAS) decline approximately 80% between the ages of 25 and 75 yr. Muscle mass and strength also decrease with aging. Published data on the effects of DHEA replacement on muscle mass and strength are conflicting. The goals of this study were to determine whether DHEA replacement increases muscle mass and strength and/or enhances the effects of heavy resistance exercise in elderly women and men. We conducted a randomized… 

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