DETERMINATION OF ELEMENTAL IMPURITIES IN SOME COMMERCIAL PAEDIATRIC AND ADULT FORMULATIONS OF ARTEMETHER – LUMEFANTRINE IN THE NIGERIAN MARKET BY ATOMIC ABSORPTION SPECTROSCOPY

@article{Awofisayo2015DETERMINATIONOE,
  title={DETERMINATION OF ELEMENTAL IMPURITIES IN SOME COMMERCIAL PAEDIATRIC AND ADULT FORMULATIONS OF ARTEMETHER – LUMEFANTRINE IN THE NIGERIAN MARKET BY ATOMIC ABSORPTION SPECTROSCOPY},
  author={S. Awofisayo and A. O. Okhamafe and Mathew I Arhewoh},
  journal={INDONESIAN JOURNAL OF PHARMACY},
  year={2015},
  volume={25},
  pages={171}
}
The composition of elemental impurities in paediatric powder for suspension (PPS) and double strength tablet (DST) commercial anti-malarial formulations of artemether-lumefantrine (AL) were determined. Six randomly selected PPS and DST products from a list of marketed products were purchased from a registered Pharmacy outlet and analyzed using flame atomic absorption spectrophotometer. The heavy metal levels were compared with the official limits for permitted daily exposure. The paediatric and… Expand

References

SHOWING 1-10 OF 14 REFERENCES
An overview of the recent trends in development of HPLC methods for determination of impurities in drugs.
A multi-element ICP-MS survey method as an alternative to the heavy metals limit test for pharmaceutical materials.
Counterfeit antimalarial drugs.
Profiling of metal ions leached from pharmaceutical packaging materials.
Preventing antimalarial drug resistance through combinations.
  • N. White
  • Biology, Medicine
  • Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
  • 1998
...
1
2
...