DET1, a negative regulator of light-mediated development and gene expression in arabidopsis, encodes a novel nuclear-localized protein

@article{Pepper1994DET1,
  title={
 DET1, a negative regulator of light-mediated development and gene expression in arabidopsis, encodes a novel nuclear-localized protein},
  author={Alan E. Pepper and Terrence P. Delaney and Tracy Washburnt and Daniel S. Poole and Joanne Chory},
  journal={Cell},
  year={1994},
  volume={78},
  pages={109-116}
}
Expression of Several Gene Sets
TLDR
Examination of deUcop mutations with respect to their effects on genes regulated by other signal transduction pathways provides evidence that DET1, COPl, and COP9 most likely act as negative regulators of severa1 sets of genes, not just those involved in light-regulated seedling development.
A role for transcriptional repression during light control of plant development
  • A. V. von Arnim, X. Deng
  • Biology
    BioEssays : news and reviews in molecular, cellular and developmental biology
  • 1996
TLDR
Rapid progress in eukaryotic gene repression mechanisms in general, and light control of plant gene expression in particular, sheds new light on how a class of ten pleiotropic COP/DET/FUS genes might function to down‐regulate light‐inducible genes in plants.
Manipulation of DET1 expression in tomato results in photomorphogenic phenotypes caused by post-transcriptional gene silencing.
TLDR
An important function for DET1 throughout plant development is indicated and silencing of DET1 in fruits results in increased carotenoids, which may have biotechnological potential.
Role of a COP1 Interactive Protein in Mediating Light-Regulated Gene Expression in Arabidopsis
TLDR
Data indicate that CIP7 acts as a positive regulator of light-regulated genes and is a potential direct downstream target of COP1 for mediating light control of gene expression.
det1, cop1, and cop9 mutations cause inappropriate expression of several gene sets.
TLDR
Examination of specificity of det/cop mutations with respect to their effects on genes regulated by other signal transduction pathways provides evidence that DET1, COP1, and COP9 most likely act as negative regulators of several sets of genes, not just those involved in light-regulated seedling development.
The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl.
TLDR
P phenotypes indicate that the HY5 gene is responsible for the regulation of fundamental developmental processes of the plant cell: cell elongation, cell proliferation, and chloroplast development.
Suppressors of an Arabidopsis thaliana phyB mutation identify genes that control light signaling and hypocotyl elongation.
TLDR
Genetic analyses show that the shy (short hypocotyl) mutations the authors have isolated fall in several loci, which suggest that some of the genes identified have functions in control of light responses.
The light-regulated Arabidopsis bZIP transcription factor gene ATB2 encodes a protein with an unusually long leucine zipper domain
TLDR
A light-regulated basic domain/leucine zipper gene, ATB2, was identified in an Arabidopsis thaliana transcription factor gene collection and transcript levels are particularly high in flowers and also light-responsive in these tissues.
Regulation of both light- and auxin-mediated development by theArabidopsis IAA3/SHY2 gene
TLDR
This work shows that the Arabidopsis shy2-1D mutation alters various light responses, including highly photomorphogenic development in darkness, and proposes that IAA3/SHY2 may integrate light signals into auxin-mediated developmental responses.
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References

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Mutations in the DET1 gene affect cell-type-specific expression of light-regulated genes and chloroplast development in Arabidopsis
  • J. Chory, C. Peto
  • Environmental Science
    Proceedings of the National Academy of Sciences of the United States of America
  • 1990
TLDR
It is suggested that the DET1 gene product is a negatively acting regulatory molecule that is used in common by the light stimulus transduction pathway and by temporal or spatial regulatory signals in plants.
A Role for Cytokinins in De-Etiolation in Arabidopsis (det Mutants Have an Altered Response to Cytokinins)
TLDR
It is shown that dark-grown wild-type seedlings exhibit similar phenotypic traits if any one of a variety of cytokinins are present in the growth medium, and a model is proposed in which light and cytokinin act independently or sequentially through common signal transduction intermediates to control the downstream light-regulated responses.
Arabidopsis ethylene-response gene ETR1: similarity of product to two-component regulators.
TLDR
An early step in ethylene signal transduction in plants may involve transfer of phosphate as in prokaryotic two-component systems.
Early auxin-induced genes encode short-lived nuclear proteins.
TLDR
It is suggested that plant tissues express short-lived nuclear proteins as a primary response to IAA and these proteins act as activators or repressors of genes responsible for mediating the various auxin responses.
HY4 gene of A. thaliana encodes a protein with characteristics of a blue-light photoreceptor
TLDR
The hy4 mutant5 is one of several mutants that are selectively insensitive to blue light during the blue-light-dependent inhibition of hypocotyl elongation response, which suggests that they lack an essential component of the cryptochrome-associated light-sensing pathway.
CA-1, a novel phosphoprotein, interacts with the promoter of the cab140 gene in Arabidopsis and is undetectable in det1 mutant seedlings.
TLDR
The lack of CA-1 activity in the det1 mutant suggests that it may function as a transcriptional repressor regulating the expression of the cab140 gene in Arabidopsis.
Light signals in leaf and chloroplast development: photoreceptors and downstream responses in search of a transduction pathway.
TLDR
This review summarizes what is known of the red- and blue-light photoreceptors that regulate dicotyledonous seedling development and the complexity of the downstream responses and places special emphasis on the recent progress made toward genetic and biochemical dissection of the signal transduction pathways.
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