DECODER : A probabilistic approach to integrate big data reveals mitochondrial Complex I as a potential Alzheimer ’ s disease therapeutic target

Identifying gene expression markers for Alzheimer’s disease (AD) neuropathology through meta-analysis is a complex undertaking because available data are often from different studies and/or brain regions involving studyspecific confounders and/or region-specific biological processes. Here we developed a probabilistic model-based framework, DECODER… CONTINUE READING