DEAF-1 function is essential for the early embryonic development of Drosophila.

@article{Veraksa2002DEAF1FI,
  title={DEAF-1 function is essential for the early embryonic development of Drosophila.},
  author={Alexey Veraksa and James A. Kennison and William McGinnis},
  journal={Genesis},
  year={2002},
  volume={33 2},
  pages={67-76}
}
The Drosophila protein DEAF-1 is a sequence-specific DNA binding protein that was isolated as a putative cofactor of the Hox protein Deformed (Dfd). In this study, we analyze the effects of loss or gain of DEAF-1 function on Drosophila development. Maternal/zygotic mutations of DEAF-1 largely result in early embryonic arrest prior to the expression of zygotic segmentation genes, although a few embryos develop into larvae with segmentation defects of variable severity. Overexpression of DEAF-1… CONTINUE READING