DEADSouth protein localizes to germ plasm and is required for the development of primordial germ cells in Xenopus laevis

@inproceedings{Yamaguchi2013DEADSouthPL,
  title={DEADSouth protein localizes to germ plasm and is required for the development of primordial germ cells in Xenopus laevis},
  author={Takuhiro Yamaguchi and Ayaka Taguchi and Kenji Watanabe and Hidehumi Orii},
  booktitle={Biology open},
  year={2013}
}
DEADSouth mRNA is a component of germ plasm in Xenopus laevis and encodes a DDX25 DEAD-box RNA helicase. To determine the intracellular localization of DEADSouth protein, we injected mRNA encoding DEADSouth tagged with mCherry fluorescent protein into fertilized eggs from transgenic Xenopus expressing EGFP fused with a mitochondrial targeting signal. The DEADSouth-mCherry fusion protein was localized to the germ plasm, a mitochondria-rich region in primordial germ cells (PGCs). DEADSouth… CONTINUE READING

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Germes is involved in translocation of germ plasm during development of Xenopus primordial germ cells.

  • The International journal of developmental biology
  • 2013
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The DEAD-box helicase Vasa: evidence for a multiplicity of functions in RNA processes and developmental biology.

  • Biochimica et biophysica acta
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