DCS‐1, DCS‐2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule

@article{Flegel2008DCS1DA,
  title={DCS‐1, DCS‐2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule},
  author={W. Flegel and I. von Zabern and A. Doescher and F. Wagner and J. Vytiskov{\'a} and M. P{\'i}{\vs}acka},
  journal={Transfusion},
  year={2008},
  volume={48}
}
BACKGROUND: RhD and RhCE are structurally related to ammonium transporter proteins, yet their physiologic function remains unclear. Recent three‐dimensional homology modeling with Escherichia coli AmtB as a template defined a putative transmembraneous channel. Three RhD variants with amino acid substitutions located at the extracellular channel aperture are described. 
24 Citations
D variants at the RhD vestibule in the weak D type 4 and Eurasian D clusters
  • 32
The DAU cluster: a comparative analysis of 18 RHD alleles, some forming partial D antigens
  • 12
Molecular genetics and clinical applications for RH.
  • W. Flegel
  • Biology, Medicine
  • Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
  • 2011
  • 118
Genetic variation of the whole ICAM4 gene in Caucasians and African Americans
  • 5
...
1
2
3
...

References

SHOWING 1-10 OF 42 REFERENCES
In‐frame triplet deletions in RHD alter the D antigen phenotype
  • 18
A DV‐like phenotype is obliteratedby A226P in the partial D DBS
  • 18
Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures.
  • I. Callebaut, F. Dulin, +5 authors J. Cartron
  • Chemistry, Medicine
  • Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
  • 2006
  • 63
Modelling the human rhesus proteins: implications for structure and function
  • 85
  • PDF
Transport characteristics of mammalian Rh and Rh glycoproteins expressed in heterologous systems.
  • C. Westhoff, D. Wylie
  • Chemistry, Medicine
  • Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
  • 2006
  • 22
Human Rhesus-associated glycoprotein mediates facilitated transport of NH(3) into red blood cells.
  • 148
  • PDF
...
1
2
3
4
5
...